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KMID : 0361720050160040322
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Korean Journal of perinatology
2005 Volume.16 No. 4 p.322 ~ p.326
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Case Reports : A Case of Lymphocytic Hypophysitis Occurred in the Second-trimester of Pregnancy
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Ko Hyun-Sun
Lee Hee-Joong
Lee Keun-Ho
Chang Eun-Deok
Kang Seok-Gu
Shin Jong-Chul
Park Tae-Chul
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Abstract
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Lymphocytic hypophysitis, a rare inflammatory disorder in the pituitary gland that is often associated with pregnancy, is caused by autoimmune destruction of the pituitary gland evidenced by diffuse lymphocytic infiltration in the pituitary gland. We report a case of lymphocytic hypophysitis in a 38-year-old woman presenting with aggravating headache and sudden visual loss during pregnancy, which was misdiagnosed as pituitary adenoma before neurosurgery. Magnetic resonance imaging, with enhancement, showed an expanding 2.5×2.0×1.7 cm sized sellar mass. The patient underwent
transsphenoidal surgery with a preoperative diagnosis of pituitary macroadenoma. A histological examination revealed diffuse lymphocytes and fibrosis of adenohypophysis with atrophy, which are characteristic of lymphocytic hypophysitis. We report a case of lymphocytic hypophysitis occurred during pregnancy with a brief review of literatures.
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KEYWORD
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Lymphocytic hypophysitis
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